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000 -- All Appnotes in One File
http://appnotes.spect-ct.com/AppNote-000-All_Appnotes_in_One_File.zip
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  All NanoSPECT application notes in one ZIP archive

This archive contains AppNotes #001 to #022 for your convenience.






file size: 30.7 MB
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099 -- Abstracts of Scientific Publications
http://appnotes.spect-ct.com/AppNote-099-Abstracts_of_Scientific_Publications.pdf
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  Bibliography with Abstracts of Multi-Pinhole SPECT Scientific Publications and Presentations
HiSPECTTM and NanoSPECT/CT® Product Applications


S. van Cauter1

(1) Bioscan, Inc., Washington D.C.


Last update: May 30, 2008

file size: 6.7 MB
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025 -- Performance-Evaluation-Small-Animal-Imaging
http://appnotes.spect-ct.com/AppNote-025-Performance-Evaluation-Small-Animal-Imaging.pdf
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  Evaluation of SPECT/CT performance for optimal small animal imaging

K. Inoue1, K. Tani2, I.O. Umeda1, M. Yamaguchi1, Y. Mutou1, M. Fukushi2, H. Fijii1

(1) Functional Imaging Division, National Cancer Center, Kashiwa, Japan (2) Division of Radiological Sciences, Tokyo Metropolitan University, Japan




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024 -- InVivo-Cationic-Liposome-in-Mice
http://appnotes.spect-ct.com/AppNote-024-InVivo-Cationic-Liposome-in-Mice.pdf
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  In Vivo Behaviour of Cationic Liposome Labeled With In-111 in Mice Using HiSPECT Technique

S.O. Viehoever1, D. Buchhold1, N.U. Schramm3, H.-W. Mueller1, O. Gottschalk2, A. Wirrwar1

(1) Dept. of Nuclear Medicine, Heinrich-Heine Universität Düsseldorf, Germany (2) Department of Surgery, LMU Munich, Germany (3) Central Institute for Electronics, FZ Jülich, Germany




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023 -- Bioscan-Observer-Study
http://appnotes.spect-ct.com/AppNote-023-Bioscan-Observer-Study.pdf
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  Inter- and intra-observer performance in a longitudinal small-animal SPECT study

J.Y. Hesterman1, B. Gershman2, C. Lackas1, K. Harlin3, J.P. Norenberg2, N.U. Schramm4, J.W. Hoppin1

(1) Bioscan, Inc. Washington D.C., USA (2) College of Pharmacy, Univ. of New Mexico, Albuquerque, NM, USA (3) inviCRO, LLC., Boston, MA, USA (4) Forschungszentrum Jülich, Germany




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022 -- London PreClinical Development
http://appnotes.spect-ct.com/AppNote-022-London_PreClinical_Development.pdf
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  High Resolution Small-Animal SPECT/CT Imaging as a Tool in Pre-Clinical Development

S.J. Mather1, J. Sosabowski1, C. Finucane1, J. Foster1, R. King1, G. Vassaux1, T. Garood2

(1) Institute of Cancer, Barts and the London School of Medicine and Dentistry, Queen Mary, University London, UK (2) William Harvey Research Institute, Queen Mary, University London, UK




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021 -- Tumor Targeting 99mTc-HYNIC peptide
http://appnotes.spect-ct.com/AppNote-021-Tumor_Targeting_99mTc-HYNIC_peptide.pdf
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  Co-complexation by histidine residues improves tumor targeting of 99mTc-HYNIC peptide conjugates

R. King1, M.B.-U. Surfraz2, P.J. Blower3, S.C.G. Giagini4, S.J. Mather1

(1) Cancer Research UK, Department of Nuclear Medicine, St. Bartholomew's Hospital, London, UK (2) Cancer Research Group, Department of Biosciences, University of Kent, UK (3) Division of Imaging Sciences, King's College London, UK (4) Functional Materials Group, University Kent, UK




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020 -- Cat brain perfusion
http://appnotes.spect-ct.com/AppNote-020-Cat_brain_perfusion.pdf
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  Cat brain perfusion with a multi-pinhole SPECT imaging system

A. Dobbeleir1, K. Audenaert1, K. Peremans1

(1) Faculty of Veterinary Medicine, University Ghent, Belgium (2) Department of Psychiatry and Medical Psychology, University Ghent, Belgium




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019 -- 5-HT2A receptor and DAT status
http://appnotes.spect-ct.com/AppNote-019-5-HT2A_receptor_and_DAT_status.pdf
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  The use of HiSPECT in the investigation of the 5-HT2A receptor and DAT status in the Mongolian gerbil

C.P.H. Moons1, K. Peremans1, K. Audenaert1, A. Dobbeleir2, E. Vandermeulen1, S. Vermeire1, F. De Vos2, E. Soenen1, H. Van Bree1, F.O. Ödberg1

(1) Faculty of Veterinary Medicine, Ghent University, Belgium (2) Faculty of Pharmaceutical Scieces, Ghent University, Belgium




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018 -- Rodent Serotonin Transporter Imaging
http://appnotes.spect-ct.com/AppNote-018-Rodent_Serotonin_Transporter_Imaging.pdf
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  Rodent serotonin transporter imaging using multi-pinhole SPECT and correlate with quantitative autoradiography

Kun-Ju Lin12, Ing-Tsung Hsiao2, Shiaw-Pyng Wey2, Yi-Hsin Weng3, Tzu-Chen Yen1

(1) Department of Nuclear Medicine and Molecular Image Center, Chang Gung Memorial Hospital, Taiwan. (2) Department of Medical Imaging and Radiological Sciences, Chang Gung University, Taiwan. (3) Department of Neurology and Neuronal Research Center, Chang Gung Memorial Hospital, Taiwan.




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017 -- Pharmacokinetis 111In CC49 Antibody
http://appnotes.spect-ct.com/AppNote-017-Pharmacokinetis_111In_CC49_Antibody.pdf
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  Multipinhole SPECT Imaging and Pharmacokinetics-by-Sacrifice of 111In Labeled CC49 Antibody in Tumored Mice

G. Liu1, P.H. Pretorius1, S. Dou1, X. Liu1, M. Rusckowski1, D.J. Hnatowich1

(1) Division of Nuclear Medicine, Department of Radiology, University of Massachusetts Medical School, Worcester




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016 -- Quantifying Radiopharma Uptake In Vivo
http://appnotes.spect-ct.com/AppNote-016-Quantifying_Radiopharma_Uptake_In_Vivo.pdf
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  Quantifying Radiopharmaceutical Uptake In Vivo Using Small-Animal SPECT/CT

B. Gershman1, J.W. Hoppin2, C. Lackas2, J.Y. Hesterman2, N.U. Schramm3, T. Anderson1, J. Howard1, L. Sklar1, J.P. Norenberg1

(1) University of New Mexico Health Sciences Center, Albuquerque, NM, USA (2) Bioscan, Inc. Washington D.C., USA (3) Forschungszentrum Jülich, Jülich, Germany




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015 -- Folate Receptor-Positive Tumors
http://appnotes.spect-ct.com/AppNote-015-Folate_Receptor-Positive_Tumors.pdf
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  Improved SPECT-Imaging of Folate Receptor-Positive Tumors in Mice Using 111In-DTPA-Folate in Combination with the Antifolate Pemetrexed

C. Müller1, R. Schibli23, F. Forrer1, E.P. Krenning1, M. de Jong1

(1) Dept. of Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands (2) Center of Radiopharmaceutical Science ETH-PSI-USZ, Villigen, Switzerland (3) Dept. of Chemistry and Applied Biosciences ETH, Zurick, Switzerland




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014 -- Folate Receptor-Positive Tumor Targeting
http://appnotes.spect-ct.com/AppNote-014-Folate_Receptor-Positive_Tumor_Targeting.pdf
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  Preclinical Evaluation of 99mTc-Histidine-Folate for Folate Receptor-Positive Tumor Targeting

C. Müller1, F. Forrer1, R. Schibli23, E.P. Krenning1, M. de Jong1

(1) Dept. of Nuclear Medicine, Erasmus Medical Center, Rotterdam, The Netherlands (2) Center of Radiopharmaceutical Science ETH-PSI-USZ, Villigen, Switzerland (3) Dept. of Chemistry and Applied Biosciences ETH, Zurick, Switzerland




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013 -- Quant Imag Mouse Thyroid 99mTc 123,131I
http://appnotes.spect-ct.com/AppNote-013-Quant_Imag_Mouse_Thyroid_99mTc_123,131I.pdf
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  Quantitative Imaging of Mouse Thyroids With 99mTc and 123,131I using NanoSPECT/CT

D. Máthé1, I. Földes2, L. Balogh1

1: National "F. Joliot-Curie" Research Inst. of Radiobiology and Radiohygiene, Budapest, Hungary 2: Central Hospital of the Ministry of Interior, Budapest, Hungary




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012 -- High-Perf SPECT-CT for Small-Animals
http://appnotes.spect-ct.com/AppNote-012-High-Perf_SPECT-CT_for_Small-Animals.pdf
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  The NanoSPECT/CT: A High-Performance SPECT/CT for Small-Animal Research

N.U. Schramm1, J.W. Hoppin2, C. Lackas2, B. Gershman3, J.P. Norenberg3, M. deJong4

1: Research Center Jülich, GER 2: Bioscan, Inc. Washington D.C., USA 3: University of New Mexico, USA 4: Erasmus Medical Center, Rotterdam, NL




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011 -- High Sensitivity Small Animal SPECT-CT
http://appnotes.spect-ct.com/AppNote-011-High_Sensitivity_Small_Animal_SPECT-CT.pdf
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  The NanoSPECT/CT: a High-Sensitivity Small-Animal SPECT/CT with Sub-millimeter Spatial Resolution

N.U. Schramm1, C. Lackas1, F. Forrer2, M. de Jong3, J.W. Hoppin3, S.C. Van Cauter3, Y.Haemisch3

1: Research Center Jülich, GER 2: Erasmus Medical Center, Rotterdam, NL 3: Bioscan, Inc. Washington D.C., USA




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010 -- X-Ray CT Component of NanoSPECT
http://appnotes.spect-ct.com/AppNote-010-X-Ray_CT_Component_of_NanoSPECT.pdf
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  The X-Ray CT Component of the NanoSPECT/CT Small-Animal Imaging System

C. Lackas1, J.W. Hoppin3, G. Németh2, I. Müller2, A. Farkas2, L. Nagy2, S. Van Cauter3, N.U. Schramm1

1: Research Center Jülich, GER 2: Mediso Ltd, Budapest, HUN 3: Bioscan, Inc. Washington D.C., USA




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009 -- MMP-SPECT vs PET
http://appnotes.spect-ct.com/AppNote-009-MMP-SPECT_vs_PET.pdf
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  How MMP-SPECT outperforms PET for non-invasive imaging of small animals

Staf C. Van Cauter, M.Sc.1, John W. Hoppin, Ph.D.1, Nils U. Schramm, Ph.D.2

1: Bioscan Inc., Washington D.C. 2: Research Center Jülich, Germany




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008 -- MMP-SPECT Application Note (4 pages)
http://appnotes.spect-ct.com/AppNote-008-MMP-SPECT_Application_Note_(4_pages).pdf
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  Multiplexed Multi-Pinhole SPECT for high-resolution, high-sensitive in vivo animal research

Nils U. Schramm Ph.D.1, Christian Lackas Ph.D.1, John W. Hoppin Ph.D.1, Staf C. Van Cauter M.Sc.2

1: Research Center Jülich, Germany 2: Bioscan Inc., Washington, D.C., USA




file size: 2.7 MB
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007 -- In Vivo Animal Imaging Goes Nano
http://appnotes.spect-ct.com/AppNote-007-In_Vivo_Animal_Imaging_Goes_Nano.pdf
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  In vivo Animal Imaging goes Nano: Now You Can Image a Mouse like a Man

Staf C. Van Cauter M.Sc.1

1: Bioscan Inc, Washington, D.C., USA




file size: 0.9 MB
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006 -- HiSPECT Module for Small-Animal Research
http://appnotes.spect-ct.com/AppNote-006-HiSPECT_Module_for_Small-Animal_Research.pdf
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  HiSPECT: A Multi-Pinhole SPECT Imaging Module for Small-Animal Research

N. Schramm1, J.W. Hoppin2, C. Lackas1, U. Engeland2, G. Ebel2, S. Van Cauter3, S. Shulman3

1: Research Center Jülich, Germany 2: Scivis GmbH, Göttingen, Germany 3: Bioscan Inc, Washington, D.C., USA




file size: 1.4 MB
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005 -- HiSPECT Translational Imaging
http://appnotes.spect-ct.com/AppNote-005-HiSPECT_Translational_Imaging.pdf
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  HiSPECT Translational Imaging: Imaging Early Arthritis in Mouse and Human

J.W. Hoppin1, C. Lackas1, A. Scherer2, A. Wirrwar2, B. Ostendorf2, N.U. Schramm1, S. Van Cauter3

1: Research Center Jülich, Germany, 2: Heinrich-Heine Universität of Düsseldorf, Germany 3: Bioscan Inc, Washington, D.C., USA




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004 -- MI Reduces Drug Development Costs
http://appnotes.spect-ct.com/AppNote-004-MI_Reduces_Drug_Development_Costs.pdf
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  How molecular imaging can help reduce drug development costs and get new treatments to market faster

S.C. Van Cauter1

1: Bioscan Inc, Washington D.C., USA




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003 -- Dual Isotope Imaging using HiSPECT
http://appnotes.spect-ct.com/AppNote-003-Dual_Isotope_Imaging_using_HiSPECT.pdf
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  HiSPECT - Dual Isotope Studies with Multiplexed Multi-Pinhole (MMPH) technique

A. Wirrwar1, S. Nikolaus1, M.Y. Noune1, N.U. Schramm2, H.-W. Müller1

1: Nuclear medicine, University hospital Düsseldorf, Germany 2: Research Center Jülich, Germany




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002 -- Hi-Res Multipinhole SPECT NS
http://appnotes.spect-ct.com/AppNote-002-Hi-Res_Multipinhole_SPECT_NS.pdf
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  HiSPECT: High-Resolution Multi-Pinhole SPECT

N. Schramm1, J.W. Hoppin1, C. Lackas1, U. Engeland2, G. Ebel2, S. Van Cauter3, S. Shulman3

1: Research Center Jülich, Germany 2: Scivis GmbH, Göttingen, Germany 3: Bioscan Inc, Washington D.C., USA




file size: 3.2 MB
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001 -- NanoSPECT-Compact SPECT Camera
http://appnotes.spect-ct.com/AppNote-001-NanoSPECT-Compact_SPECT_Camera.pdf
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  NanoSPECT: A Compact Multi-Pinhole SPECT Camera with Sub-Millimeter Resolution for Small-Animal Imaging

C. Lackas1, N.U. Schramm1, J.W. Hoppin1, H. Halling1

1: Research Center Jülich, Germany




file size: 3.2 MB
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